Fermentative production of L-arginine. II. Mechanism of L-arginine production by L-arginine-producing mutants of Corynebacterium glutamicum.
نویسندگان
چکیده
منابع مشابه
Production of L-arginine by arginine hydroxamate-resistant mutants of Bacillus subtilis.
l-Arginine hydroxamate inhibited the growth of various bacteria, and the inhibition was readily reversed by arginine. l-Arginine hydroxamate (10(-3)m) completely inhibited the growth of Bacillus subtilis. This inhibitory effect was prevented by 2.5 x 10(-4)ml-arginine, which was the most effective of all the natural amino acids in reversing the inhibition. l-Arginine hydroxamate-resistant mutan...
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Toward the creation of a robust and efficient producer of L-arginine and L-citrulline (arginine/citrulline), we have performed reengineering of a Corynebacterium glutamicum strain by using genetic information of three classical producers. Sequence analysis of their arg operons identified three point mutations (argR123, argG92(up), and argG45) in one producer and one point mutation (argB26 or ar...
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As a result of impressive progress that made in economic traits such as body weight gain, feed efficiency and breast yield to meet the demands of consumers, nowadays, poultry became more susceptible to obesity, stressors and less ability to resist the common diseases in commercial farms. L-Arginine (L-Arg) supplementation in poultry diets improves egg production, egg weight, modulates lipid met...
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Introduction L-Arginine is a semi-essential amino acid involved in numerous areas of human physiology, including production of nitric oxide (NO) – a key messenger molecule involved in vascular regulation, immune activity, and endocrine function. Arginine is also involved in protein production, wound healing, erectile function, and fertility. Arginine is not considered essential because humans c...
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The present review will give an overview of the biochemistry and metabolism of L-arginine focusing on the mechanisms which may either provide or limit cellular availability of this amino acid for nitric oxide synthases and arginase / polyamine pathway and describe possible interactions between these pathways. In addition, emerging species differences in the expression and role of arginases are ...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1979
ISSN: 0002-1369,1881-1280
DOI: 10.1271/bbb1961.43.105